Before it was approved for use in food and beverage products, aspartame was subjected to one of the most comprehensive testing programs ever undertaken for a food additive. More than 200 scientific studies have been conducted with laboratory animals and a cross-section of men, women and children. Based on these extensive studies, aspartame's safety has been confirmed by the United States Food and Drug Administration (FDA), by Health Canada, by the European Food Safety Authority (EFSA), by the Joint Expert Committee on Food Additives (JECFA) of the United Nations Food & Agriculture Organization and the World Health Organization, and by more than 100 national regulatory agencies.

Health professional organizations, including the American Medical Association, the American Diabetes Association and the American Dietetic Association, have reviewed the science and support the safety and use of aspartame.

The FDA considers aspartame to be one of the most thoroughly tested and studied food additives the agency has ever approved. Writing in FDA Consumer in 1998, Dr. David Hattan confirmed that the agency had reviewed more than 100 toxicological and clinical studies and had concluded that aspartame is safe for the general population.

Click on the links on the right to read about some of the key scientific papers on weight control, diabetes care and safety. Alternatively, this site has a searchable database of abstracts from the scientific literature that address questions that are sometimes asked about aspartame. Simply enter the appropriate term in the search box below.