Aspartame Research Library
Search abstracts
Research area: Methanol, Formaldehyde and Formic Acid
Metabolism of aspartame and its L-phenylalanine methyl ester decomposition product by the porcine gut. Burgert SL, Andersen DW, Stegink LD, Takeuchi H, Schedl HP. Metabolism. 1991 Jun;40(6):612-8.
Cytotoxic effects of methanol, formaldehyde, and formate on dissociated rat thymocytes: a possibility of aspartame toxicity. Oyama Y, Sakai H, Arata T, Okano Y, Akaike N, Sakai K, Noda K. Cell Biol Toxicol. 2002;18(1):43-50.
Comparative metabolism of aspartame in experimental animals and humans. Ranney RE, Oppermann JA, Muldoon E, McMahon FG. J Toxicol Environ Health. 1976 Nov;2(2):441-51.
Blood methanol concentrations in normal adult subjects administered abuse doses of aspartame. Stegink LD, Brummel MC, McMartin K, Martin-Amat G, Filer LJ Jr, Baker GL, Tephly TR. J Toxicol Environ Health. 1981 Feb;7(2):281-90.
Blood methanol concentrations in one-year-old infants administered graded doses of aspartame. Stegink LD, Brummel MC, Filer LJ Jr, Baker GL. J Nutr. 1983 Aug;113(8):1600-6.
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults. Stegink LD, Filer LJ Jr, Bell EF, Ziegler EE, Tephly TR. Metabolism. 1989 Apr;38(4):357-63.
Comments on the purported generation of formaldehyde and adduct formation from the sweetener aspartame. Tephly TR. Life Sci. 1999;65(13):PL157-60.